| Division | Equipe 1 | Equipe 2 | Date | Heure | Salle |
| DMU17-P2 | CSSL SAUSHEIM – 1 | COLMAR BASKET – 2 | 01/05/2022 | 16:00 | COSEC |
| DM4 | MULHOUSE PBA – 6 | COLMAR BASKET – 3 | 30/04/2022 | 20:00 | GYMNASE MARCEL TSCHANZ |
| RMU15-P2 | COLMAR BASKET | FURDENHEIM A.C.S.L. | 30/04/2022 | 14:00 | GYMNASE CAMILLE SÉE |
| RMU17-P2 | COLMAR BASKET | STRASBOURG SAINT JOSEPH | 30/04/2022 | 16:00 | GYMNASE CAMILLE SÉE |
| RMU13-P2 | IE – CTC ALLIANCE SPORT ALSACE | COLMAR BASKET | 30/04/2022 | 16:30 | MAISON DES SPORTS |
| PRF | EN – CTC de l’ILL – 2 | COLMAR BASKET | 30/04/2022 | 18:30 | GYMNASE PIERRE DE COUBERTIN |
| DM3 | BLOTZHEIM REGIO BASKET CLUB | COLMAR BASKET – 2 | 01/05/2022 | 10:00 | PALAIS BEAU BOURG |
| RM2 | STRASBOURG SAINT JOSEPH – 2 | COLMAR BASKET | 01/05/2022 | 17:30 | CENTRE SPORTIF ESPLANADE |
| DFU18-P2 | FCSL EGUISHEIM | COLMAR BASKET | 01/05/2022 | 17:30 | CENTRE SPORTIF LA TUILERIE |
| DFU11-P2 | AS HORBOURG-WIHR – 2 | COLMAR BASKET | 30/04/2022 | 15:00 | SALLE POLYVALENTE ALFRED KASTLER |
| DMU11-P2 | BASKET CLUB DE KINGERSHEIM – 1 | COLMAR BASKET – 2 | 30/04/2022 | 16:00 | COSEC DE KINGERSHEIM |
| DFU13-P2 | FCSL EGUISHEIM | COLMAR BASKET | 30/04/2022 | 16:30 | CENTRE SPORTIF LA TUILERIE |
| DMU13-P2 | COLMAR BASKET – 2 | CS SAINT PP WALDIGHOFFEN | 01/05/2022 | 14:00 | GYMNASE PFEFFEL |
| DMU11-P2 | EN – CTC THUR DOLLER – 1 | COLMAR BASKET – 1 | 01/05/2022 | 16:00 | 1- COSEC GRANDE SALLE |
| DXU9-P2 | AS HORBOURG-WIHR | COLMAR BASKET | 30/04/2022 | 13:30 | SALLE POLYVALENTE ALFRED KASTLER |
| DMU15-P2 | COLMAR BASKET – 2 | FCSL EGUISHEIM – 1 | 01/05/2022 | 16:00 | GYMNASE PFEFFEL |
| DFU15-P2 | BLOTZHEIM REGIO BASKET CLUB | COLMAR BASKET | 30/04/2022 | 16:30 | PALAIS BEAU BOURG |
